Uncovering neuroinflammation-related modules and potential repurposing drugs for Alzheimer's disease through multi-omics data integrative analysis

Uncovering neuroinflammation-related modules and potential repurposing drugs for Alzheimer's disease through multi-omics data integrative analysis

BackgroundNeuroinflammation is one of the key factors leading to neuron death and synapse dysfunction in Alzheimer's disease (AD). Amyloid-β (Aβ) is thought to have an association with microglia activation and trigger neuroinflammation in AD. However, inflammation response in brain disorders is...

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Bibliographic Details
Main Authors: Shensuo Li, Changhao Lu, Zhenzhen Zhao, Dong Lu, Guangyong Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer's disease
neuroinflammation
amyloid-β
data integration
drug repurposing
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1161405/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1161405/full

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