Mice deficient in complement C3 are protected against recognition memory deficits and astrogliosis induced by status epilepticus

Mice deficient in complement C3 are protected against recognition memory deficits and astrogliosis induced by status epilepticus

IntroductionStatus epilepticus (SE) can significantly increase the risk of temporal lobe epilepsy (TLE) and cognitive comorbidities. A potential candidate mechanism underlying memory defects in epilepsy may be the immune complement system. The complement cascade, part of the innate immune system, mo...

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Bibliographic Details
Main Authors: Nicole D. Schartz, Alisha Aroor, Yibo Li, Nicole Pinzón-Hoyos, Amy L. Brewster
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
complement
epilepsy
memory
astrocytes
pilocarpine
hippocampus
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1265944/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2023.1265944/full

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