Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers

Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers

Many mutation analyses of the HBV genome have been performed in the search for new prognostic markers. However, the Kozak sequence preceding precore was covered only infrequently in these analyses. In this study, the HBV core promoter/precore region was sequenced in serum samples from European inact...

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Bibliographic Details
Main Authors: Kai-Henrik Peiffer, Catrina Spengler, Michael Basic, Bingfu Jiang, Lisa Kuhnhenn, Wiebke Obermann, Tobias Zahn, Mirco Glitscher, Alessandro Loglio, Floriana Facchetti, Gert Carra, Alica Kubesch, Johannes Vermehren, Viola Knop, Christiana Graf, Julia Dietz, Fabian Finkelmeier, Eva Herrmann, Jonel Trebicka, Arnold Grünweller, Stefan Zeuzem, Christoph Sarrazin, Pietro Lampertico, Eberhard Hildt
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-11-01
Series:JCI Insight
Subjects:
Hepatology
Virology
Online Access:https://doi.org/10.1172/jci.insight.135833

Internet

https://doi.org/10.1172/jci.insight.135833

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