Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: A novel mechanism of haemostasis

The podoplanin-CLEC-2 axis is critical in mice for prevention of hemorrhage in the cerebral vasculature during mid-gestation. This raises the question as to how platelets are captured by podoplanin on neuroepithelial cells in a high shear environment. In this study, we demonstrate that mouse platele...

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Bibliographic Details
Main Authors: Stephanie E. Lombard, Alice Y. Pollitt, Craig E. Hughes, Ying Di, Tom Mckinnon, Chris A. O’callaghan, Steve P. Watson
Format: Article
Language:English
Published: Taylor & Francis Group 2018-10-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2017.1356919