aKmerBroom: Ancient oral DNA decontamination using Bloom filters on k-mer sets

aKmerBroom: Ancient oral DNA decontamination using Bloom filters on k-mer sets

Summary: Dental calculus samples are modeled as a mixture of DNA coming from dental plaque and contaminants. Current computational decontamination methods such as Recentrifuge and DeconSeq require either a reference database or sequenced negative controls, and therefore have limited use cases. We pr...

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Bibliographic Details
Main Authors: Camila Duitama González, Samarth Rangavittal, Riccardo Vicedomini, Rayan Chikhi, Hugues Richard
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:iScience
Subjects:
Microbial genomics
Biocomputational method
Sequence analysis
Paleogenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422302134X

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http://www.sciencedirect.com/science/article/pii/S258900422302134X

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