Multi-Layer Nanofibrous PCL Scaffold-Based Colon Cancer Cell Cultures to Mimic Hypoxic Tumor Microenvironment for Bioassay

Multi-Layer Nanofibrous PCL Scaffold-Based Colon Cancer Cell Cultures to Mimic Hypoxic Tumor Microenvironment for Bioassay

Three-dimensional (3D) cancer cell culture systems have been developed to aid the study of molecular mechanisms in cancer development, identify therapeutic targets, and test drug candidates. In this study, we developed a strategy for mimicking the hypoxic tumor microenvironment in a 3D cancer cell c...

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Bibliographic Details
Main Authors: Eun-Taex Oh, Ha Gyeong Kim, Min-Ho Choi, Jae-Seon Lee, Sang Jeong Kim, Jong-Young Kwak, Heon Joo Park
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
cancer cell culture
hypoxia
nanofibrous scaffold
PCL
three-dimensional
Online Access:https://www.mdpi.com/2072-6694/13/14/3550

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https://www.mdpi.com/2072-6694/13/14/3550

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