Deoxycholic Acid Upregulates Serum Golgi Protein 73 through Activating NF-κB Pathway and Destroying Golgi Structure in Liver Disease

Deoxycholic Acid Upregulates Serum Golgi Protein 73 through Activating NF-κB Pathway and Destroying Golgi Structure in Liver Disease

Golgi protein 73 (GP73) is upregulated in a variety of liver diseases, yet the detailed mechanism is poorly characterized. We analyzed GP73 in a retrospective cohort including 4211 patients with chronic liver disease (CLD) or hepatocellular carcinoma (HCC). The effect of deoxycholic acid (DCA) and n...

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Bibliographic Details
Main Authors: Danli Yang, Mingjie Yao, Ying Yan, Yanna Liu, Xiajie Wen, Xiangmei Chen, Fengmin Lu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biomolecules
Subjects:
liver disease
bile acids
Golgi protein 73
deoxycholic acid
nuclear factor-kappa B
Online Access:https://www.mdpi.com/2218-273X/11/2/205

Internet

https://www.mdpi.com/2218-273X/11/2/205

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