Parkin-Dependent Mitophagy Is Required for the Inhibition of ATF4 on NLRP3 Inflammasome Activation in Cerebral Ischemia-Reperfusion Injury in Rats

<b>Background</b>: Nod-like receptor protein 3 (NLRP3) inflammasome is a crucial contributor in the inflammatory process during cerebral ischemia/reperfusion (I/R) injury. ATF4 plays a pivotal role in the pathogenesis of cerebral I/R injury, however, its function and underlying mechanism...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Qi He, Zhenyu Li, Changchang Meng, Jingxian Wu, Yong Zhao, Jing Zhao
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2019-08-01
Цуврал:Cells
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/2073-4409/8/8/897