TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst

TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst

Our understanding of the antigen presentation pathway has recently been enhanced with the identification that the tapasin-related protein TAPBPR is a second major histocompatibility complex (MHC) class I-specific chaperone. We sought to determine whether, like tapasin, TAPBPR can also influence MHC...

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Bibliographic Details
Main Authors: Clemens Hermann, Andy van Hateren, Nico Trautwein, Andreas Neerincx, Patrick J Duriez, Stefan Stevanović, John Trowsdale, Janet E Deane, Tim Elliott, Louise H Boyle
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-10-01
Series:eLife
Subjects:
antigen processing and presentation
MHC
peptide repertoire
Online Access:https://elifesciences.org/articles/09617

Internet

https://elifesciences.org/articles/09617

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