Effect of salinomycin on EMT and stemness pathways in 5-FU-resistant breast cancer

Effect of salinomycin on EMT and stemness pathways in 5-FU-resistant breast cancer

Cancer stem cells (CSCs) present in tumours are the primary cause of cancer recurrence and mediates resistance against therapeutic intervention. CSC properties like epithelial-to-mesenchymal transition (EMT) and cancer stemness lead to metastasis, quiescence and clonogenicity. Thus, there is a need...

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Bibliographic Details
Main Authors: Divya Sivanesan, Raj Pranap Arun, Rama Shanker Verma
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Advances in Cancer Biology - Metastasis
Subjects:
Cancer relapse
Cancer stem cells
Drug resistance
EMT
Stemness
Salinomycin
Online Access:http://www.sciencedirect.com/science/article/pii/S2667394021000046

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http://www.sciencedirect.com/science/article/pii/S2667394021000046

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