End-point determination of heterogeneous formulations using inline torque measurements for a high-shear wet granulation process

In this study, the torque profiles of heterogeneous granulation formulations with varying powder properties in terms of particle size, solubility, deformability, and wettability, were studied, and the feasibility of identifying the end-point of the granulation process for each formulation based on t...

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Bibliographic Details
Main Authors: Ashley Dan, Haresh Vaswani, Alice Šimonová, Aleksandra Grząbka-Zasadzińska, Jingzhe Li, Koyel Sen, Shubhajit Paul, Yin-Chao Tseng, Rohit Ramachandran
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156723000324