Proneoplastic effects of PGE<sub>2 </sub>mediated by EP4 receptor in colorectal cancer

<p>Abstract</p> <p>Background</p> <p>Prostaglandin E<sub>2 </sub>(PGE<sub>2</sub>) is the major product of Cyclooxygenase-2 (COX-2) in colorectal cancer (CRC). We aimed to assess PGE<sub>2 </sub>cell surface receptors (EP 1–4) to exam...

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Bibliographic Details
Main Authors: Malhotra Vikrum, Molloy Eamonn S, Byrne Sinead M, Doherty Glen A, Austin Sandra C, Kay Elaine W, Murray Frank E, Fitzgerald Desmond J
Format: Article
Language:English
Published: BMC 2009-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/207