Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates.

Upon exposure to DNA damaging agents, Saccharomyces cerevisiae respond by activating a massive transcriptional program that reflects the fact that "DNA damaging" agents also damage other cellular macromolecules. To identify the transcriptional response that is specific to DNA damage, we ha...

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Bibliographic Details
Main Authors: Ivan Rusyn, Rebecca C Fry, Thomas J Begley, Joanna Klapacz, J Peter Svensson, Mark Ambrose, Leona D Samson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2080756?pdf=render