Monitoring tacrolimus whole blood concentrations
Tacrolimus (TAC) is the primary drug for most immunosuppressive therapy regimens. It has a narrow therapeutic index, meaning that insufficient dose can lead to graft and tissue rejection, while overdose can lead to increased risk of infections, toxicity, and cancerous tumors in organ transplant reci...
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Format: | Article |
Language: | Russian |
Published: |
Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2020-07-01
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Series: | Vestnik Transplantologii i Iskusstvennyh Organov |
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Online Access: | https://journal.transpl.ru/vtio/article/view/1198 |