Preclinical Efficacy of a Trivalent Human FcγRI-Targeted Adjuvant-Free Subunit Mucosal Vaccine against Pulmonary Pneumococcal Infection

Lack of safe and effective mucosal adjuvants has severely hampered the development of mucosal subunit vaccines. In this regard, we have previously shown that immunogenicity of vaccine antigens can be improved by targeting the antigens to the antigen-presenting cells. Specifically, groups of mice imm...

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Bibliographic Details
Main Authors: Sudeep Kumar, Raju Sunagar, Edmund J. Gosselin
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/2/193