Impaired mitochondrial dynamics and removal of the damaged mitochondria in diabetic retinopathy

IntroductionMitochondrial dynamic plays a major role in their quality control, and the damaged mitochondrial components are removed by autophagy. In diabetic retinopathy, mitochondrial fusion enzyme, mitofusin 2 (Mfn2), is downregulated and mitochondrial dynamic is disturbed resulting in depolarized...

Full description

Bibliographic Details
Main Authors: Kumari Alka, Jay Kumar, Renu A. Kowluru
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1160155/full