Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting <i>Pseudomonas aeruginosa</i> and <i>Salmonella</i> Typhimurium

Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting <i>Pseudomonas aeruginosa</i> and <i>Salmonella</i> Typhimurium

The prevalence of bacterial pathogens being resistant to antibiotic treatment is increasing worldwide, leading to a severe global health challenge. Simultaneously, the development and approval of new antibiotics stagnated in the past decades, leading to an urgent need for novel approaches to avoid t...

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Bibliographic Details
Main Authors: Julia von Ambüren, Fynn Schreiber, Julia Fischer, Sandra Winter, Edeltraud van Gumpel, Alexander Simonis, Jan Rybniker
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Microorganisms
Subjects:
multidrug-resistant pathogens
host-directed therapies
antibiotic drug screening
<i>Salmonella</i> Typhimurium
<i>Pseudomonas aeruginosa</i>
type 3 secretion system
Online Access:https://www.mdpi.com/2076-2607/8/8/1096

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https://www.mdpi.com/2076-2607/8/8/1096

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