The Confounder-Mediator Dilemma: Should We Control for Obesity to Estimate the Effect of Perfluoroalkyl Substances on Health Outcomes?

The Confounder-Mediator Dilemma: Should We Control for Obesity to Estimate the Effect of Perfluoroalkyl Substances on Health Outcomes?

Confounding adjustment is important for observational studies to derive valid effect estimates for inference. Despite the theoretical advancement of confounding selection procedure, it is often challenging to distinguish between confounders and mediators due to the lack of information about the time...

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Bibliographic Details
Main Authors: Kosuke Inoue, Atsushi Goto, Takehiro Sugiyama, Cecilia Høst Ramlau-Hansen, Zeyan Liew
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Toxics
Subjects:
confounder
mediator
perfluoroalkyl substances
body mass index
Danish National Birth Cohort
National Health and Nutrition Examination Survey
Online Access:https://www.mdpi.com/2305-6304/8/4/125

Internet

https://www.mdpi.com/2305-6304/8/4/125

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