Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions

Distinct dissociation rates of murine and human norovirus P-domain dimers suggest a role of dimer stability in virus-host interactions

NMR and native mass spectrometry reveal that the major capsid VP1 protein from murine and human norovirus exhibit distinct behaviors and are differentially regulated by the binding of glycochenodeoxycholic acid.

Bibliographic Details
Main Authors: Robert Creutznacher, Thorben Maass, Jasmin Dülfer, Clara Feldmann, Veronika Hartmann, Miranda Sophie Lane, Jan Knickmann, Leon Torben Westermann, Lars Thiede, Thomas J. Smith, Charlotte Uetrecht, Alvaro Mallagaray, Christopher A. Waudby, Stefan Taube, Thomas Peters
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03497-4

Internet

https://doi.org/10.1038/s42003-022-03497-4

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