Hijacking the Fusion Complex of Human Parainfluenza Virus as an Antiviral Strategy

Hijacking the Fusion Complex of Human Parainfluenza Virus as an Antiviral Strategy

ABSTRACT The receptor binding protein of parainfluenza virus, hemagglutinin-neuraminidase (HN), is responsible for actively triggering the viral fusion protein (F) to undergo a conformational change leading to insertion into the target cell and fusion of the virus with the target cell membrane. For...

Full description

Bibliographic Details
Main Authors: T. C. Marcink, E. Yariv, K. Rybkina, V. Más, F. T. Bovier, A. des Georges, A. L. Greninger, C. A. Alabi, M. Porotto, N. Ben-Tal, A. Moscona
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mBio
Subjects:
antiviral agents
cryo-electron tomography
viral fusion protein
viral protein structure
viral receptor
Online Access:https://journals.asm.org/doi/10.1128/mBio.03203-19

Internet

https://journals.asm.org/doi/10.1128/mBio.03203-19

Similar Items