The prognostic role of single cell invasion and nuclear diameter in early oral tongue squamous cell carcinoma

Abstract Background The clinical significance of single cell invasion and large nuclear diameter is not well documented in early-stage oral tongue squamous cell carcinoma (OTSCC). Methods We used hematoxylin and eosin-stained sections to evaluate the presence of single cell invasion and large nuclei...

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Bibliographic Details
Main Authors: Alhadi Almangush, Jaana Hagström, Caj Haglund, Luiz Paulo Kowalski, Ricardo D. Coletta, Antti A. Mäkitie, Tuula Salo, Ilmo Leivo
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-024-11954-y