Blood Levels of the <i>SMOC1</i> Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study

Hepatokines are liver-derived proteins that may influence metabolic pathways such as insulin sensitivity. Recently, Sparc-related modular calcium-binding protein 1 (SMOC1) was identified as glucose-responsive hepatokine that is dysregulated in the setting of non-alcoholic fatty liver disease (NAFLD)...

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Bibliographic Details
Main Authors: Nooshin Ghodsian, Eloi Gagnon, Jérôme Bourgault, Émilie Gobeil, Hasanga D. Manikpurage, Nicolas Perrot, Arnaud Girard, Patricia L. Mitchell, Benoit J. Arsenault
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/13/12/4208