Treatment of steroid-refractory graft versus host disease in children

Treatment of steroid-refractory graft versus host disease in children

Systemic steroids are still the first-line approach in acute graft-versus-host disease (aGvHD), and the backbone of chronic GvHD management. Refractoriness to steroid represent a major cause of morbidity and non-relapse mortality after hematopoietic stem cell transplantation (HSCT). In both backgrou...

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Bibliographic Details
Main Authors: Francesca Gottardi, Davide Leardini, Edoardo Muratore, Francesco Baccelli, Sara Cerasi, Francesco Venturelli, Andrea Zanaroli, Tamara Belotti, Arcangelo Prete, Riccardo Masetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Transplantation
Subjects:
GvHD
steroid-refractory
children
pediatric HSCT
ruxolitinib
Online Access:https://www.frontiersin.org/articles/10.3389/frtra.2023.1251112/full

Internet

https://www.frontiersin.org/articles/10.3389/frtra.2023.1251112/full

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