Tailoring DNA vaccines: designing strategies against HER2 positive cancers

Tailoring DNA vaccines: designing strategies against HER2 positive cancers

The crucial role of HER2 in epithelial transformation and its selective overexpression on cancer tissues makes it an ideal target for cancer immunotherapies such as passive immunotherapy with Trastuzumab. There are, however, a number of concerns regarding the use of monoclonal antibodies which inclu...

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Bibliographic Details
Main Authors: Cristina eMarchini, Cristina eKalogris, Chiara eGarulli, lucia ePietrella, Federico eGabrielli, Claudia eCurcio, Elena eQuaglino, Federica eCavallo, Augusto eAmici
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Oncology
Subjects:
Immunotherapy
breast cancer
HER2
immunological tolerance
DNA Vaccines
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00122/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00122/full

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