Protamine dose to neutralize heparin at the completion of cardiopulmonary bypass can be reduced significantly without affecting post-operative bleeding

Protamine dose to neutralize heparin at the completion of cardiopulmonary bypass can be reduced significantly without affecting post-operative bleeding

Background: Systemic anticoagulation with heparin during cardiopulmonary bypass (CPB) should be neutralized by protamine administration to restore normal hemostasis. Our previous study showed the protamine-to-heparin ratio (P-to-H) of 1:1 (1 mg protamine:100 IU circulating heparin; 1.0 Ratio) is lik...

Full description

Bibliographic Details
Main Authors: Lee Min-Ho, Beck Matthew, Shann Kenneth
Format: Article
Language:English
Published: EDP Sciences 2023-09-01
Series:The Journal of ExtraCorporeal Technology
Subjects:
protamine-to-heparin ratio
protamine dose
post-operative bleeding
heparin protamine titration
cardiopulmonary bypass
Online Access:https://ject.edpsciences.org/articles/ject/full_html/2023/03/ject230010/ject230010.html

Internet

https://ject.edpsciences.org/articles/ject/full_html/2023/03/ject230010/ject230010.html

Similar Items