Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni.

Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni.

Cercarial elastase is the major invasive larval protease in Schistosoma mansoni, a parasitic blood fluke, and is essential for host skin invasion. Genome sequence analysis reveals a greatly expanded family of cercarial elastase gene isoforms in Schistosoma mansoni. This expansion appears to be uniqu...

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Bibliographic Details
Main Authors: Jessica R Ingram, Salma B Rafi, A Alegra Eroy-Reveles, Manisha Ray, Laura Lambeth, Ivy Hsieh, Debbie Ruelas, K C Lim, Judy Sakanari, Charles S Craik, Matthew P Jacobson, James H McKerrow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3317910?pdf=render

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http://europepmc.org/articles/PMC3317910?pdf=render

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