Metabolic study of breast MCF-7 tumour spheroids after gamma irradiation by 1H NMR spectroscopy and microimaging.

Metabolic study of breast MCF-7 tumour spheroids after gamma irradiation by 1H NMR spectroscopy and microimaging.

Multicellular tumour spheroids are an important model system to investigate the response of tumour cells to radio- and chemotherapy. They share more properties with the original tumor than cells cultured as 2D monolayers do, which helps distinguish the intrinsic properties of monolayer cells from th...

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Bibliographic Details
Main Authors: Alessandra ePalma, Sveva eGrande, Anna Maria Luciani, Vladimír eMlynárik, Laura eGuidoni, Vincenza eViti, Antonella eRosi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Oncology
Subjects:
Radiation
metabolism.
MR spectroscopy
spheroids
mobile lipids
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00105/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00105/full

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