Nanomechanics of the endothelial glycocalyx in experimental sepsis.

The endothelial glycocalyx (eGC), a carbohydrate-rich layer lining the luminal side of the endothelium, regulates vascular adhesiveness and permeability. Although central to the pathophysiology of vascular barrier dysfunction in sepsis, glycocalyx damage has been generally understudied, in part beca...

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Bibliographic Details
Main Authors: Anne Wiesinger, Wladimir Peters, Daniel Chappell, Dominik Kentrup, Stefan Reuter, Hermann Pavenstädt, Hans Oberleithner, Philipp Kümpers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3835794?pdf=render