Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors

<p>Abstract</p> <p>Background</p> <p>Evolution of DNA polymerases, the key enzymes of DNA replication and repair, is central to any reconstruction of the history of cellular life. However, the details of the evolutionary relationships between DNA polymerases of archaea...

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Bibliographic Details
Main Authors: Pavlov Youri I, Rogozin Igor B, Makarova Kira S, Tahirov Tahir H, Koonin Eugene V
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/4/1/11