Targeting Nup358/RanBP2 by a viral protein disrupts stress granule formation.

Viruses have evolved mechanisms to modulate cellular pathways to facilitate infection. One such pathway is the formation of stress granules (SG), which are ribonucleoprotein complexes that assemble during translation inhibition following cellular stress. Inhibition of SG assembly has been observed u...

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Bibliographic Details
Main Authors: Jibin Sadasivan, Marli Vlok, Xinying Wang, Arabinda Nayak, Raul Andino, Eric Jan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010598