Shikonin promotes hypertrophic scar repair by autophagy of hypertrophic scar-derived fibroblasts
ABSTRACT Purpose: To investigate the Shikonin (SHI) induce autophagy of hypertrophic scar-derived fibroblasts (HSFs) and the mechanism of which in repairing hypertrophic scar. Methods: This study showed that SHI induced autophagy from HSFs and repaired skin scars through the AMPK/mTOR pathway. Ala...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2023-10-01
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Series: | Acta Cirúrgica Brasileira |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502023000100237&lng=en&tlng=en |