ω-Transaminase-Mediated Asymmetric Synthesis of (<i>S</i>)-1-(4-Trifluoromethylphenyl)Ethylamine

The pivotal role played by ω-transaminases (ω-TAs) in the synthesis of chiral amines used as building blocks for drugs and pharmaceuticals is widely recognized. However, chiral bulky amines are challenging to produce. Herein, a ω-TA (TR<sub>8</sub>) from a marine bacterium was used to sy...

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Bibliographic Details
Main Authors: Carlos J. C. Rodrigues, Manuel Ferrer, Carla C. C. R. de Carvalho
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/11/3/307