Third time's a charm: diagnosis of herpes simplex encephalitis after two negative polymerase chain reaction results

Introduction: Polymerase chain reaction (PCR) testing of cerebrospinal fluid (CSF) is a sensitive and specific method in diagnosing herpes simplex virus (HSV) encephalitis. However there are increasing reports of false negative HSV PCR. Case description: We present a patient in the 9th decade of lif...

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Bibliographic Details
Main Authors: Mahbobeh Niksefat, Daniel Guillen, Pouria Moshayedi, Charles R. Rinaldo, Ajitesh Ojha
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020310914