Radiation Necrosis Following Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy with High Biologically Effective Doses for Large Brain Metastases

Radiation Necrosis Following Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy with High Biologically Effective Doses for Large Brain Metastases

In Radiation Therapy Oncology Group 90-05, the maximum tolerated dose of single-fraction radiosurgery (SRS) for brain metastases of 21–30 mm was 18 Gy (biologically effective dose (BED) 45 Gy<sub>12</sub>). Since the patients in this study received prior brain irradiation, tolerable BED...

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Bibliographic Details
Main Authors: Leonie Johannwerner, Elisa M. Werner, Oliver Blanck, Stefan Janssen, Florian Cremers, Nathan Y. Yu, Dirk Rades
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biology
Subjects:
brain metastasis
radiation necrosis
stereotactic radiosurgery
fractionated stereotactic radiotherapy
biologically effective dose
Online Access:https://www.mdpi.com/2079-7737/12/5/655

Internet

https://www.mdpi.com/2079-7737/12/5/655

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