Flexibility and Preorganization of Fluorescent Nucleobase-Pyrene Conjugates Control DNA and RNA Recognition

Flexibility and Preorganization of Fluorescent Nucleobase-Pyrene Conjugates Control DNA and RNA Recognition

We synthesized a new amino acid-fluorescent nucleobase derivative (qAN1-AA) and from it two new fluorescent nucleobase–fluorophore (pyrene) conjugates, whereby only the analogue with the longer and more flexible linker (qAN1-pyr2) self-folded into intramolecularly stacked qAN1/pyrene conformation, y...

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Bibliographic Details
Main Authors: Željka Ban, Josipa Matić, Biserka Žinić, Anders Foller Füchtbauer, L. Marcus Wilhelmsson, Ivo Piantanida
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
DNA/RNA recognition
hydrogen bonding
fluorescent nucleobase
pyrene
intramolecular pre-organization
Online Access:https://www.mdpi.com/1420-3049/25/9/2188

Internet

https://www.mdpi.com/1420-3049/25/9/2188

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