Inhibition of endothelial activation: a new way to treat cerebral malaria?

BACKGROUND: Malaria is still a major public health problem, partly because the pathogenesis of its major complication, cerebral malaria (CM), remains incompletely understood. However tumor necrosis factor (TNF) is thought to play a key role in the development of this neurological syndrome, as well a...

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Bibliographic Details
Main Authors: Samuel C Wassmer, George J Cianciolo, Valéry Combes, Georges E Grau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-09-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1188254?pdf=render