The Right-Handed Parallel β-Helix Topology of <i>Erwinia chrysanthemi</i> Pectin Methylesterase Is Intimately Associated with Both Sequential Folding and Resistance to High Pressure

The complex topologies of large multi-domain globular proteins make the study of their folding and assembly particularly demanding. It is often characterized by complex kinetics and undesired side reactions, such as aggregation. The structural simplicity of tandem-repeat proteins, which are characte...

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Bibliographic Details
Main Authors: Jessica Guillerm, Jean-Marie Frère, Filip Meersman, André Matagne
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/8/1083