Ketogenic diet enhances the effects of oxycodone in mice

Abstract Opioids have been used to manage pain for thousands of years, but they have significant potential for abuse. Prescription opioids, like oxycodone, are associated with 32% of overdoses, that have reached a total of 75,673 deaths in 2021. A major challenge is maximizing their therapeutic pote...

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Bibliographic Details
Main Authors: R. Trinko, D. M. Diaz, E. Foscue, S. L. Thompson, J. R. Taylor, R. J. DiLeone
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-33458-8