Polymorphic Molecular Signatures in Variable Regions of the <i>Plasmodium falciparum var2csa</i> DBL3x Domain Are Associated with Virulence in Placental Malaria
The <i>Plasmodium falciparum</i> protein VAR2CSA allows infected erythrocytes to accumulate within the placenta, inducing pathology and poor birth outcomes. Multiple exposures to placental malaria (PM) induce partial immunity against VAR2CSA, making it a promising vaccine candidate. Howe...
Main Authors: | Eldin Talundzic, Stephen Scott, Simon O. Owino, David S. Campo, Naomi W. Lucchi, Venkatachalam Udhayakumar, Julie M. Moore, David S. Peterson |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-04-01
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Series: | Pathogens |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-0817/11/5/520 |
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