Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in male mice with obesity

Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in male mice with obesity

Abstract There are epidemiological associations between obesity and type 2 diabetes, cardiovascular disease and Alzheimer’s disease. The role of amyloid beta 42 (Aβ42) in these diverse chronic diseases is obscure. Here we show that adipose tissue releases Aβ42, which is increased from adipose tissue...

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Bibliographic Details
Main Authors: Liam G. Hall, Juliane K. Czeczor, Timothy Connor, Javier Botella, Kirstie A. De Jong, Mark C. Renton, Amanda J. Genders, Kylie Venardos, Sheree D. Martin, Simon T. Bond, Kathryn Aston-Mourney, Kirsten F. Howlett, James A. Campbell, Greg R. Collier, Ken R. Walder, Matthew McKenzie, Mark Ziemann, Sean L. McGee
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44520-4

Internet

https://doi.org/10.1038/s41467-023-44520-4

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