Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks

Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks

DNA double-strand breaks (DSBs) elicit the so-called DNA damage response (DDR), largely relying on ataxia telangiectasia mutated (ATM) and DNA-dependent protein kinase (DNA-PKcs), two members of the PI3K-like kinase family, whose respective functions during the sequential steps of the DDR remains co...

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Bibliographic Details
Main Authors: Pierre Caron, Jonathan Choudjaye, Thomas Clouaire, Béatrix Bugler, Virginie Daburon, Marion Aguirrebengoa, Thomas Mangeat, Jason S. Iacovoni, Alejandro Álvarez-Quilón, Felipe Cortés-Ledesma, Gaëlle Legube
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Cell Reports
Subjects:
DSB repair
chromatin
PI 3-kinases
γH2AX
ChIP-chip
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471501178X

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http://www.sciencedirect.com/science/article/pii/S221112471501178X

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