Vitronectin promotes immunothrombotic dysregulation in the venular microvasculature

Vitronectin promotes immunothrombotic dysregulation in the venular microvasculature

Microvascular immunothrombotic dysregulation is a critical process in the pathogenesis of severe systemic inflammatory diseases. The mechanisms controlling immunothrombosis in inflamed microvessels, however, remain poorly understood. Here, we report that under systemic inflammatory conditions the ma...

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Bibliographic Details
Main Authors: Bernd Uhl, Florian Haring, Julia Slotta-Huspenina, Joshua Luft, Vera Schneewind, Jonas Hildinger, Zhengquan Wu, Katja Steiger, Bojan Smiljanov, Aarif M. N. Batcha, Oliver T. Keppler, Johannes C. Hellmuth, Tobias Lahmer, Konrad Stock, Bernhard G. Weiss, Martin Canis, Konstantin Stark, Thomas Bromberger, Markus Moser, Christian Schulz, Wilko Weichert, Gabriele Zuchtriegel, Christoph A. Reichel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
immunothrombosis
platelets
neutrophils
microvasculature
systemic inflammation
SIRS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1078005/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1078005/full

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