HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

Carbohydrate response element–binding protein (ChREBP) is a carbohydrate-sensing transcription factor that regulates both adaptive and maladaptive genomic responses in coordination of systemic fuel homeostasis. Genetic variants in the ChREBP locus associate with diverse metabolic traits in humans, i...

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Podrobná bibliografie
Hlavní autoři: Ashot Sargsyan, Ludivine Doridot, Sarah A. Hannou, Wenxin Tong, Harini Srinivasan, Rachael Ivison, Ruby Monn, Henry H. Kou, Jonathan M. Haldeman, Michelle Arlotto, Phillip J. White, Paul A. Grimsrud, Inna Astapova, Linus T. Tsai, Mark A. Herman
Médium: Článek
Jazyk:English
Vydáno: American Society for Clinical investigation 2023-01-01
Edice:JCI Insight
Témata:
Metabolism
On-line přístup:https://doi.org/10.1172/jci.insight.153740

Internet

https://doi.org/10.1172/jci.insight.153740

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