A pilot study: effect of irisin on trabecular bone in a streptozotocin-induced animal model of type 1 diabetic osteopathy utilizing a micro-CT

Background Osteoporosis is a significant co-morbidity of type 1 diabetes mellitus (DM1) leading to increased fracture risk. Exercise-induced hormone ‘irisin’ in low dosage has been shown to have a beneficial effect on bone metabolism by increasing osteoblast differentiation and reducing osteoclast m...

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Bibliographic Details
Main Authors: Sahar Mohsin, Fiona Brock, Suneesh Kaimala, Charlene Greenwood, Mohsin Sulaiman, Keith Rogers, Ernest Adeghate
Format: Article
Language:English
Published: PeerJ Inc. 2023-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/16278.pdf