Blood-stage malaria vaccines: post-genome strategies for the identification of novel vaccine candidates

Blood-stage malaria vaccines: post-genome strategies for the identification of novel vaccine candidates

Introduction: An efficacious malaria vaccine is necessary to advance the current control measures towards malaria elimination. To-date, only RTS,S/AS01, a leading pre-erythrocytic stage vaccine completed phase 3 trials, but with an efficacy of 28–36% in children, and 18–26% in infants, that waned ov...

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Bibliographic Details
Main Authors: Edward H. Ntege, Eizo Takashima, Masayuki Morita, Hikaru Nagaoka, Tomoko Ishino, Takafumi Tsuboi
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:Expert Review of Vaccines
Subjects:
antibody profiling
malaria vaccine
plasmodium falciparum
post-genome
protein array
reverse vaccinology
wheat germ cell-free protein synthesis system
Online Access:http://dx.doi.org/10.1080/14760584.2017.1341317

Internet

http://dx.doi.org/10.1080/14760584.2017.1341317

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