Mechanistic Insights into the Metabolic Pathways Using High-Resolution Mass Spectrometry and Predictive Models in Pancreatic β-Cell Lines (β-TC-6)

Objectives: We have previously shown that inhibition of the mTORC1 nutrient-sensing complex by rapamycin and mTORC1/mTORC2 inhibition by either Torin-2 or RapaLink-1 have differential effects on the global untargeted metabolomics in in vivo and in vitro cell culture models. Methods: In this study, w...

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Bibliographic Details
Main Authors: Ghada A. Soliman, Ye He, Rinat Abzalimov
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biology and Life Sciences Forum
Subjects:
Online Access:https://www.mdpi.com/2673-9976/29/1/16