A drug cocktail for protecting against ischemia-reperfusion injury
Ischemia followed by reperfusion (I/R) of cardiomyocytes causes release of a large amount of inducible nitric oxide (NO) synthase (iNOS) followed by an increase of asymmetric dimethylarginine (ADMA). ADMA disrupts NO signaling by switching of the NOS activity from NO to the production of reactive ox...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
IMR Press
2020-01-01
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| Series: | Frontiers in Bioscience-Landmark |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/FBL/25/4/10.2741/4831 |