TRIM59-mediated ferroptosis enhances neuroblastoma development and chemosensitivity through p53 ubiquitination and degradation

TRIM59-mediated ferroptosis enhances neuroblastoma development and chemosensitivity through p53 ubiquitination and degradation

Neuroblastoma, predominantly afflicting young individuals, is characterized as an embryonal tumor, with poor prognosis primarily attributed to chemoresistance. This study delved into the impact of tripartite motif (TRIM) 59, an E3 ligase, on neuroblastoma development and chemosensitivity through med...

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Bibliographic Details
Main Authors: Yingbei Liu, Na Jiang, Weicheng Chen, Wenbo Zhang, Xiao Shen, Bing Jia, Gang Chen
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Neuroblastoma
TRIM59
Ferroptosis
Lipid ROS
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024020450

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024020450

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