Fusobacterium nucleatum facilitates proliferation and autophagy by activating miR-361-3p/NUDT1 axis through oxidative stress in hypopharyngeal squamous cell carcinoma

Fusobacterium nucleatum facilitates proliferation and autophagy by activating miR-361-3p/NUDT1 axis through oxidative stress in hypopharyngeal squamous cell carcinoma

Abstract Background To investigate how Fusobacterium nucleatum (Fn) promotes oxidative stress and mediates proliferation and autophagy in hypopharyngeal squamous cell carcinoma (HPSCC). Methods The prognosis for 82 HPSCC cases was retrospectively analyzed. HPSCC cell line FaDu was co-cultured with F...

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Bibliographic Details
Main Authors: Hui-Ching Lau, Xiaohui Yuan, Huiying Huang, Ming Zhang, Chi-Yao Hsueh, Hongli Gong
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Cancer
Subjects:
Hypopharyngeal squamous cell carcinoma
Fusobacterium nucleatum
miR-361-3p
Autophagy
Oxidative stress
Online Access:https://doi.org/10.1186/s12885-023-11439-4

Internet

https://doi.org/10.1186/s12885-023-11439-4

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