Elevated rates of sister chromatid exchange at chromosome ends.
Chromosome ends are known hotspots of meiotic recombination and double-strand breaks. We monitored mitotic sister chromatid exchange (SCE) in telomeres and subtelomeres and found that 17% of all SCE occurs in the terminal 0.1% of the chromosome. Telomeres and subtelomeres are significantly enriched...
| Auteurs principaux: | , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Public Library of Science (PLoS)
2007-02-01
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| Collection: | PLoS Genetics |
| Accès en ligne: | http://europepmc.org/articles/PMC1802831?pdf=render |